Journal article
HLA-associated viral polymorphism in chronically HIV-1-infected Japanese cohort: analysis of four-digit HLA allele level
Retrovirology, Vol.9(Suppl 2)
2012
Abstract
It is assumed that the difference of HLA class I distribution among ethnic populations influences HIV evolution because HLA-restricted immune pressure selects escape mutations. Approximately 50% of HLA class I alleles are shared between Japanese and Caucasians. The analysis of HLA-associated polymorphism (HLA-AP) in both Japanese and Caucasian infected with clade B virus is expected to clarify the difference of HIV-1 evolution between both populations.
Details
- Title
- HLA-associated viral polymorphism in chronically HIV-1-infected Japanese cohort: analysis of four-digit HLA allele level
- Authors/Creators
- T. Chikata (Author/Creator)J.M. Carlson (Author/Creator)Y. Tamura (Author/Creator)Z.L. Brumme (Author/Creator)T. Naruto (Author/Creator)M. Hashimoto (Author/Creator)M.A. Borghan (Author/Creator)M. John (Author/Creator)S. Mallal (Author/Creator)H. Gatanaga (Author/Creator)S. Oka (Author/Creator)M. Yakiguchi (Author/Creator)
- Publication Details
- Retrovirology, Vol.9(Suppl 2)
- Publisher
- BioMed Central
- Number of pages
- 1
- Identifiers
- 991005542661407891
- Copyright
- © 2012 Chikata et al
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
- Note
- Poster Presentation at AIDS Vaccine 2012, Boston, 9-12 September, 2012.
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- Web Of Science research areas
- Virology
- ESI research areas
- Microbiology