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Hereditary hemochromatosis in the post-HFE era
Journal article   Open access   Peer reviewed

Hereditary hemochromatosis in the post-HFE era

J.K. Olynyk, D. Trinder, G.A. Ramm, R.S. Britton and B.R. Bacon
Hepatology, Vol.48(3), pp.991-1001
2008
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Abstract

Following the discovery of the HFE gene in 1996 and its linkage to the iron overload disorder hereditary hemochromatosis (HH) there have been profound developments in our understanding of the pathogenesis of the biochemical and clinical manifestations of a number of iron overload disorders. This article provides an update of recent developments and key issues relating to iron homeostasis and inherited disorders of iron overload, with emphasis on HFE-related HH, and is based on the content of the American Association for the Study of Liver Diseases Single Topic Conference entitled “Hemochromatosis: What has Happened after HFE?” which was held at the Emory Convention Center in Atlanta, September 7-9, 2007.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.184 Physiology & Metals
1.184.573 Iron Metabolism
Web Of Science research areas
Gastroenterology & Hepatology
ESI research areas
Clinical Medicine
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