High Fasting Plasma Glucose, Diabetes, and Its Risk Factors in the Eastern Mediterranean Region, 1990-2013: Findings From the Global Burden of Disease Study 2013

Maziar Moradi-Lakeh; Mohammad Hossein Forouzanfar; Charbel El Bcheraoui; Farah Daoud; Ashkan Afshin; Sarah Wulf Hanson; Theo Vos; Mohsen Naghavi; Christopher J L Murray; Ali H Mokdad; Global Burden of Disease Collaborators on Eastern Mediterranean Region and Diabetes; Khurshid Alam

doi:10.2337/dc16-1075

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High Fasting Plasma Glucose, Diabetes, and Its Risk Factors in the Eastern Mediterranean Region, 1990-2013: Findings From the Global Burden of Disease Study 2013

Journal article

Open access

Peer reviewed

High Fasting Plasma Glucose, Diabetes, and Its Risk Factors in the Eastern Mediterranean Region, 1990-2013: Findings From the Global Burden of Disease Study 2013

Maziar Moradi-Lakeh, Mohammad Hossein Forouzanfar, Charbel El Bcheraoui, Farah Daoud, Ashkan Afshin, Sarah Wulf Hanson, Theo Vos, Mohsen Naghavi, Christopher J L Murray, Ali H Mokdad, …

Diabetes care, Vol.40(1), pp.22-29

2017

DOI: https://doi.org/10.2337/dc16-1075

PMID: 27797926

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Abstract

Adult

Aged

Blood Glucose - analysis

Diabetes Mellitus - blood

Diabetes Mellitus - etiology

Diabetes Mellitus - mortality

Fasting - blood

Female

Global Burden of Disease - statistics & numerical data

Humans

Male

Mediterranean Region - epidemiology

Middle Aged

Prevalence

Quality-Adjusted Life Years

Risk Factors

The prevalence of diabetes in the Eastern Mediterranean Region (EMR) is among the highest in the world. We used findings from the Global Burden of Disease 2013 study to calculate the burden of diabetes in the EMR. The burden of diabetes and burden attributable to high fasting plasma glucose (HFPG) were calculated for each of the 22 countries in the EMR between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, deaths, and disability-adjusted life years (DALYs). The diabetes death rate increased by 60.7%, from 12.1 per 100,000 population (95% uncertainty interval [UI]: 11.2-13.2) in 1990 to 19.5 per 100,000 population (95% UI: 17.4-21.5) in 2013. The diabetes DALY rate increased from 589.9 per 100,000 (95% UI: 498.0-698.0) in 1990 to 883.5 per 100,000 population (95% UI: 732.2-1,051.5) in 2013. In 2013, HFPG accounted for 4.9% (95% UI: 4.4-5.3) of DALYs from all causes. Total DALYs from diabetes increased by 148.6% during 1990-2013; population growth accounted for a 62.9% increase, and aging and increase in age-specific DALY rates accounted for 31.8% and 53.9%, respectively. Our findings show that diabetes causes a major burden in the EMR, which is increasing. Aging and population growth do not fully explain this increase in the diabetes burden. Programs and policies are urgently needed to reduce risk factors for diabetes, increase awareness of the disease, and improve diagnosis and control of diabetes to reduce its burden.

Details

Title: High Fasting Plasma Glucose, Diabetes, and Its Risk Factors in the Eastern Mediterranean Region, 1990-2013: Findings From the Global Burden of Disease Study 2013
Authors/Creators: Maziar Moradi-Lakeh - Institute for Health Metrics and Evaluation
Mohammad Hossein Forouzanfar - University of Washington
Charbel El Bcheraoui - University of Washington
Farah Daoud - University of Washington
Ashkan Afshin - University of Washington
Sarah Wulf Hanson - Institute for Health Metrics and Evaluation
Theo Vos - University of Washington
Mohsen Naghavi - University of Washington
Christopher J L Murray - University of Washington
Ali H Mokdad - Institute for Health Metrics and Evaluation
Global Burden of Disease Collaborators on Eastern Mediterranean Region and Diabetes
Khurshid Alam - Centre for Healthy Ageing
Publication Details: Diabetes care, Vol.40(1), pp.22-29
Identifiers: 991005591578207891
Murdoch Affiliation: Centre for Healthy Ageing
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.26 Diabetes; 1.26.42 Diabetes Management
Web Of Science research areas: Endocrinology & Metabolism
ESI research areas: Clinical Medicine