Journal article
High-resolution HLA-DQB1 typing using the polymerase chain reaction and sequence-specific primers
Tissue Antigens, Vol.50(6), pp.688-692
1997
Abstract
Polymorphism at HLA-DQB1 is known to influence tissue compatibility and disease susceptibility; however, current DQB1 typing methods are unable to distinguish the 32 currently recognized DQB1 alleles. We have developed a 32-reaction PCR-SSP method capable of differentiating all DQB1 alleles that differ in amino acid sequence. This method can resolve all heterozygous combinations of DQB1 alleles, with the exception of several combinations involving alleles not thus far detected in Caucasoid populations.
Details
- Title
- High-resolution HLA-DQB1 typing using the polymerase chain reaction and sequence-specific primers
- Authors/Creators
- C.G. Mullighan (Author/Creator) - Churchill HospitalM. Bunce (Author/Creator) - Churchill HospitalK.I. Welsh (Author/Creator) - Churchill Hospital
- Publication Details
- Tissue Antigens, Vol.50(6), pp.688-692
- Publisher
- Blackwell Publishing
- Identifiers
- 991005544306407891
- Copyright
- 1997 Munksgaard
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Citation topics
- 1 Clinical & Life Sciences
- 1.6 Immunology
- 1.6.607 MHC Diversity
- Web Of Science research areas
- Cell Biology
- Immunology
- Pathology
- ESI research areas
- Molecular Biology & Genetics