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Hospital-onset Gram-negative Surveillance Program annual report, 2011
Journal article   Open access   Peer reviewed

Hospital-onset Gram-negative Surveillance Program annual report, 2011

J.D. Turnidge, T. Gottlieb, D.H. Mitchell, G.W. Coombs, J.C. Pearson and J.M. for the Australian Group on Antimicrobial Resistance Bell
Communicable diseases intelligence quarterly report, Vol.38(1), pp.E49-E53
2014
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Abstract

The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2011 survey focussed on hospital-onset infections, examining isolates from all specimens presumed to be causing disease. In 2011, 1,827 Escherichia coli, 537 Klebsiella species and 269 Enterobacter species were tested using a commercial automated method (Vitek 2, BioMérieux) and results were analysed using Clinical and Laboratory Standards Institute breakpoints from January 2012. Of the key resistances, non-susceptibilty to the third-generation cephalosporin, ceftriaxone, was found in 9.6% of E. coli and 9.5%–12.1% ofKlebsiella spp. Non-susceptibility rates to ciprofloxacin were 10.6% for E. coli, 0.0%–8.3% for Klebsiella spp. and 0.0%–5.0% in Enterobacter spp. Resistance rates to gentamicin were 8.6%, 2.9%–10.9%, and 0.0%–15.6% for the same 3 groups respectively. Eight strains, 5 Klebsiella spp. and 3 Enterobacter spp. were shown to harbour a carbapenemase (IMP-4).

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