Host adaptation and host-parasite co-evolution in Cryptosporidium: Implications for taxonomy and public health

L. Xiao; I. Sulaiman; U.M. Ryan; L. Zhou; E.R. Atwill; M.L. Tischler; X. Zhang; R. Fayer; A.A. Lal

doi:10.1016/S0020-7519(02)00197-2

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Host adaptation and host-parasite co-evolution in Cryptosporidium: Implications for taxonomy and public health

Journal article

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Host adaptation and host-parasite co-evolution in Cryptosporidium: Implications for taxonomy and public health

L. Xiao, I. Sulaiman, U.M. Ryan, L. Zhou, E.R. Atwill, M.L. Tischler, X. Zhang, R. Fayer and A.A. Lal

International Journal for Parasitology, Vol.32(14), pp.1773-1785

19/12/2002

DOI: https://doi.org/10.1016/S0020-7519(02)00197-2

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Abstract

To assess the genetic diversity and evolution of Cryptosporidium parasites, the partial ssrRNA, actin, and 70 kDa heat shock protein (HSP70) genes of 15 new Cryptosporidium parasites were sequenced. Sequence data were analysed together with those previously obtained from other Cryptosporidium parasites (10 Cryptosporidium spp. and eight Cryptosporidium genotypes). Results of this multi-locus genetic characterisation indicate that host adaptation is a general phenomenon in the genus Cryptosporidium, because specific genotypes were usually associated with specific groups of animals. On the other hand, host-parasite co-evolution is also common in Cryptosporidium, as closely related hosts usually had related Cryptosporidium parasites. Results of phylogenetic analyses suggest that the Cryptosporidium parvum bovine genotype and Cryptosporidium meleagridis were originally parasites of rodents and mammals, respectively, but have subsequently expanded their host ranges to include humans. Understanding the evolution of Cryptosporidium species is important not only for clarification of the taxonomy of the parasites but also for assessment of the public health significance of Cryptosporidium parasites from animals.

Details

Title: Host adaptation and host-parasite co-evolution in Cryptosporidium: Implications for taxonomy and public health
Authors/Creators: L. Xiao (Author/Creator) - United States Department of Health and Human Services
I. Sulaiman (Author/Creator) - United States Department of Health and Human Services
U.M. Ryan (Author/Creator) - Murdoch University
L. Zhou (Author/Creator) - United States Department of Health and Human Services
E.R. Atwill (Author/Creator) - University of California, Davis
M.L. Tischler (Author/Creator) - Benedictine University
X. Zhang (Author/Creator) - Changchun University
R. Fayer (Author/Creator) - United States Department of Agriculture
A.A. Lal (Author/Creator) - United States Department of Health and Human Services
Publication Details: International Journal for Parasitology, Vol.32(14), pp.1773-1785
Publisher: Elsevier BV
Identifiers: 991005544214107891
Copyright: © 2002 Australian Society for Parasitology Inc. Published by Elsevier Science Ltd. All rights reserved.
Murdoch Affiliation: State Agricultural Biotechnology Centre
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.246 Diarrheal Diseases; 1.246.985 Cryptosporidium
Web Of Science research areas: Parasitology
ESI research areas: Microbiology