How Synthesis of Algal Nanoparticles Affects Cancer Therapy? – A Complete Review of the Literature

Mostafa El-Sheekh; Samar Sami AlKafaas; Hadeer Rady; Bassant E Abdelmoaty; Heba M Bedair; Abdelhamid A Ahmed; Mohamed T El-Saadony; Synan F AbuQamar; Khaled A El-Tarabily

doi:10.2147/IJN.S423171

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How Synthesis of Algal Nanoparticles Affects Cancer Therapy? – A Complete Review of the Literature

Journal article

Open access

Peer reviewed

How Synthesis of Algal Nanoparticles Affects Cancer Therapy? – A Complete Review of the Literature

Mostafa El-Sheekh, Samar Sami AlKafaas, Hadeer Rady, Bassant E Abdelmoaty, Heba M Bedair, Abdelhamid A Ahmed, Mohamed T El-Saadony, Synan F AbuQamar and Khaled A El-Tarabily

International journal of nanomedicine, Vol.18, pp.6601-6638

2023

DOI: https://doi.org/10.2147/IJN.S423171

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Abstract

algae

metabolites

cancer therapy

green synthesis

medical applications

nanoparticles

The necessity to engineer sustainable nanomaterials for the environment and human health has recently increased. Due to their abundance, fast growth, easy cultivation, biocompatibility and richness of secondary metabolites, algae are valuable biological source for the green synthesis of nanoparticles (NPs). The aim of this review is to demonstrate the feasibility of using algal-based NPs for cancer treatment. Blue-green, brown, red and green micro- and macro-algae are the most commonly participating algae in the green synthesis of NPs. In this process, many algal bioactive compounds, such as proteins, carbohydrates, lipids, alkaloids, flavonoids and phenols, can catalyze the reduction of metal ions to NPs. In addition, many driving factors, including pH, temperature, duration, static conditions and substrate concentration, are involved to facilitate the green synthesis of algal-based NPs. Here, the biosynthesis, mechanisms and applications of algal-synthesized NPs in cancer therapy have been critically discussed. We also reviewed the effective role of algal synthesized NPs as anticancer treatment against human breast, colon and lung cancers and carcinoma.

Details

Title: How Synthesis of Algal Nanoparticles Affects Cancer Therapy? – A Complete Review of the Literature
Authors/Creators: Mostafa El-Sheekh
Samar Sami AlKafaas - Tanta University
Hadeer Rady - Tanta University
Bassant E Abdelmoaty - Tanta University
Heba M Bedair - Tanta University
Abdelhamid A Ahmed - Tanta University
Mohamed T El-Saadony
Synan F AbuQamar - United Arab Emirates University
Khaled A El-Tarabily
Publication Details: International journal of nanomedicine, Vol.18, pp.6601-6638
Publisher: Dove Press
Number of pages: 38
Grant note: Abu Dhabi Award for Research Excellence-Department of Education and Knowledge: 21S105 Khalifa Center for Biotechnology and Genetic Engineering-UAEU: 31R286
This review was funded by Abu Dhabi Award for Research Excellence-Department of Education and Knowledge (Grant #: 21S105) to K El-Tarabily, and Khalifa Center for Biotechnology and Genetic Engineering-UAEU (Grant #: 31R286) to S. AbuQamar.
Identifiers: 991005616558507891
Murdoch Affiliation: Centre for Terrestrial Ecosystem Science and Sustainability
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 2 Chemistry; 2.67 Nanoparticles; 2.67.231 Nanotoxicology
Web Of Science research areas: Nanoscience & Nanotechnology; Pharmacology & Pharmacy
ESI research areas: Pharmacology & Toxicology