Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation

Zoya Gridneva; Wan J Tie; Alethea Rea; Ching Tat Lai; Leigh C Ward; Kevin Murray; Peter E Hartmann; Donna T Geddes

doi:10.3390/nu10091332

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Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation

Journal article

Open access

Peer reviewed

Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation

Zoya Gridneva, Wan J Tie, Alethea Rea, Ching Tat Lai, Leigh C Ward, Kevin Murray, Peter E Hartmann and Donna T Geddes

Nutrients, Vol.10(9), 1332

2018

DOI: https://doi.org/10.3390/nu10091332

PMCID: PMC6164442

PMID: 30235880

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Abstract

casein

whey

protein

breastfeeding

infant

body composition

bioelectrical impedance spectroscopy

ultrasound skinfolds

human milk

calculated daily intakes

lactation

Human milk (HM) influences infant feeding patterns and body composition (BC). This small proof-of concept longitudinal study investigated relationships between infant/maternal BC and HM casein, whey and total protein during the first 12 months of lactation. BC of breastfeeding dyads (n = 20) was measured at 2 (n = 15), 5 (n = 20), 9 (n = 19), and/or 12 (n = 18) months postpartum with ultrasound skinfolds (infants) and bioimpedance spectroscopy (infants/mothers). Proteins concentrations and 24-h milk intake were measured and calculated daily intakes (CDI) determined. Higher maternal weight, body mass index, fat-free mass, fat-free mass index, and fat mass index were associated with higher concentration of whey protein (p ≤ 0.034, n = 20). There were no associations between infant BC and concentrations of all proteins, and CDI of whey and total protein. Higher CDI of casein were associated with lower infant fat-free mass (p = 0.003, n = 18) and higher fat mass (p < 0.001), fat mass index (p = 0.001, n = 18), and % fat mass (p < 0.001, n = 18) measured with ultrasound skinfolds. These results show a differential effect of HM casein on development of infant BC during the first year of life, suggesting that there is a potential to improve outcome for the infant through interventions, such as continuation of breastfeeding during the first 12 months of life and beyond, which may facilitate favourable developmental programming that could reduce risk of non-communicable diseases later in life.

Details

Title: Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation
Authors/Creators: Zoya Gridneva - The University of Western Australia
Wan J Tie - The University of Western Australia
Alethea Rea - The University of Western Australia
Ching Tat Lai - The University of Western Australia
Leigh C Ward - The University of Queensland
Kevin Murray - The University of Western Australia
Peter E Hartmann - The University of Western Australia
Donna T Geddes - The University of Western Australia
Publication Details: Nutrients, Vol.10(9), 1332
Publisher: MDPI
Grant note: APA Award / The University of Western Australia an unrestricted research grant / Medela AG, Switzerland
Identifiers: 991005579925207891
Murdoch Affiliation: School of Mathematics, Statistics, Chemistry and Physics; Centre for Terrestrial Ecosystem Science and Sustainability
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.72 Obstetrics & Gynecology; 1.72.891 Breastfeeding
Web Of Science research areas: Nutrition & Dietetics
ESI research areas: Agricultural Sciences