Logo image
Humoral immunity in disseminated Aspergillus terreus infection in the dog
Journal article   Peer reviewed

Humoral immunity in disseminated Aspergillus terreus infection in the dog

M.J. Day and W.J. Penhale
Veterinary Microbiology, Vol.16(3), pp.283-94
03/1988
url
Link to Published Version *Subscription may be requiredView

Abstract

Aspects of humoral immunity were studied in 17 dogs with disseminated aspergillosis (16 cases Aspergillus terreus, 1 case Aspergillus flavipes). All dogs had markedly raised serum IgG levels by single radial immunodiffusion (range 1500-6000 mg dl-1). Despite this, serum antibody to A. terreus was demonstrated in only 7/16 cases by agar gel diffusion, 9/16 cases by counter immunoelectrophoresis, 10/16 by ELISA and 11/16 by an indirect immunofluorescence assay. Serum antibody was also detected in 2/5 clinically normal relatives of 2 cases, indicating previous exposure or subclinical infection.

Details

Metrics

23 Record Views
Logo image