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Identification and characterization of aldehyde oxidases (AOXs) in the cotton bollworm
Journal article   Open access   Peer reviewed

Identification and characterization of aldehyde oxidases (AOXs) in the cotton bollworm

W. Xu and Y. Liao
The Science of Nature, Vol.104(11-12)
2017
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Abstract

Aldehyde oxidases (AOXs) are a family of metabolic enzymes that oxidize aldehydes into carboxylic acids; therefore, they play critical roles in detoxification and degradation of chemicals. By using transcriptomic and genomic approaches, we successfully identified six putative AOX genes (HarmAOX1-6) from cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). In silico expression profile, reverse transcription (RT)-PCR, and quantitative PCR (qPCR) analyses showed that HarmAOX1 is highly expressed in adult antennae, tarsi, and larval mouthparts, so they may play an important role in degrading plant-derived compounds. HarmAOX2 is highly and specifically expressed in adult antennae, suggesting a candidate pheromone-degrading enzyme (PDE) to inactivate the sex pheromone components (Z)-11-hexadecenal and (Z)-9-hexadecenal. RNA sequencing data further demonstrated that a number of host plants they feed on could significantly upregulate the expression levels of HarmAOX1 in larvae. This study improves our understanding of insect aldehyde oxidases and insect-plant interactions.

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Citation topics
3 Agriculture, Environment & Ecology
3.220 Smell & Taste Science
3.220.701 Olfactory Systems
Web Of Science research areas
Biochemistry & Molecular Biology
ESI research areas
Plant & Animal Science
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