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Identification and isolation of rodent lung dendritic cells
Journal article   Peer reviewed

Identification and isolation of rodent lung dendritic cells

P.A. Stumbles, J. Thomas and P.G. Holt
Dendritic Cell Protocols, Vol.64, pp.73-83
2001
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Abstract

Dendritic cells (DC) are a trace cell population found in most tissues that display potent antigen acquisition and presentation capabilities and are unique among antigen-presenting-cell types in their ability to activate unprimed T cells (1). DC are particularly prominent at the mucosal surfaces of the lung and gastrointestinal tract, where they are thought to play a critical role in the regulation of immune responses to environmental antigens (2-4).

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