Journal article
Identification of a new HLA-B*39 allele: HLA-B*3924
Tissue Antigens, Vol.56(2), pp.178-179
2000
Abstract
We have identified a new HLA-B*39 allele through polymerase chain reaction (PCR) using sequence-specific primers (SSP) and sequence-based typing of exons 2 and 3. This novel allele was identified in three HLA-identical siblings of Turkish origin. This allele only differs from HLA-B*3903 at a unique single nucleotide substitution (T for C) at position 365 in exon 3 which results in an amino acid change in codon 98 of methionine (ATG) to threonine (ACG). The sequencing enabled the development of a monospecific PCR-SSP reaction which can be used to discriminate between HLA-B*3924 and other B*39 alleles.
Details
- Title
- Identification of a new HLA-B*39 allele: HLA-B*3924
- Authors/Creators
- J.T. Cook (Author/Creator) - Churchill HospitalS. Day (Author/Creator) - United Kingdom Transplant Support Service Authority, Stoke Gifford, Bristol, United KingdomP.P.J. Dunn (Author/Creator) - United Kingdom Transplant Support Service Authority, Stoke Gifford, Bristol, United KingdomK.I. Welsh (Author/Creator) - Churchill HospitalM. Bunce (Author/Creator) - Churchill Hospital
- Publication Details
- Tissue Antigens, Vol.56(2), pp.178-179
- Publisher
- Blackwell Publishing
- Identifiers
- 991005540199207891
- Copyright
- 2000 Munksgaard
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
28 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Citation topics
- 1 Clinical & Life Sciences
- 1.6 Immunology
- 1.6.607 MHC Diversity
- Web Of Science research areas
- Cell Biology
- Immunology
- Pathology
- ESI research areas
- Molecular Biology & Genetics