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Immunopathology of experimental Jembrana disease in Bali cattle
Journal article   Peer reviewed

Immunopathology of experimental Jembrana disease in Bali cattle

D.M.N. Dharma, P.W. Ladds, G.E. Wilcox and R.S.F. Campbell
Veterinary Immunology and Immunopathology, Vol.44(1), pp.31-44
1994
DOI: https://doi.org/10.1016/0165-2427(94)90167-8
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Abstract

Sequential immunohistochemical studies of the lymphoreticular responses of Bali cattle (Bos javanicus syn. Bos sondaicus) after inoculation with the Jembrana disease virus were carried out using the peroxidase-antiperoxidase test for immunoglobulin containing cell assessment and the indirect immunoperoxidase test for lymphocyte subset assessment. The prevalence of immunoglobulin G-containing cells declined during the acute phase of the disease but became significantly elevated during convalescence. This trend was consistent with serological responses previously observed using an enzyme linked immunosorbent assay. Temporary immunosuppression appeared to occur during the acute phase of the disease as indicated by a decrease in the immunoglobulin G-containing cells in the lymphoid organs and an observed decrease in the BoCD4/BoC8 lymphocyte ratio in lymph node follicles.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.66 HIV
1.66.46 HIV Pathogenesis
Web Of Science research areas
Immunology
Veterinary Sciences
ESI research areas
Plant & Animal Science
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