Journal article
In vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes and other filamentous fungi
The Journal of antimicrobial chemotherapy, Vol.50(2), pp.195-199
08/2002
Abstract
The in vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes (n = 106) and filamentous fungi (n = 78) was determined. Tea tree oil MICs for all fungi ranged from 0.004% to 0.25% and minimum fungicidal concentrations (MFCs) ranged from <0.03% to 8.0%. Time-kill experiments with 1-4 x MFC demonstrated that three of the four test organisms were still detected after 8 h of treatment, but not after 24 h. Comparison of the susceptibility to tea tree oil of germinated and non-germinated Aspergillus niger conidia showed germinated conidia to be more susceptible than non-germinated conidia. These data demonstrate that tea tree oil has both inhibitory and fungicidal activity.
Details
- Title
- In vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes and other filamentous fungi
- Authors/Creators
- K.A. Hammer (Author/Creator)C.F. Carson (Author/Creator)T.V. Riley (Author/Creator)
- Publication Details
- The Journal of antimicrobial chemotherapy, Vol.50(2), pp.195-199
- Publisher
- Oxford University Press
- Identifiers
- 991005540157407891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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