Journal article
In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin
Journal of Antimicrobial Chemotherapy, Vol.59(3), pp.553-555
2007
Abstract
Objectives: Eumycetoma caused by Madurella mycetomatis is treated with surgery and high doses of itraconazole and ketoconazole. These agents are toxic, and new therapies are required.
Methods: MICs were determined for artemisinin and tea tree oil, two natural herbal compounds.
Results: Artemisinin was not active against M. mycetomatis, but tea tree oil did inhibit its growth. Since tea tree oil's prime component easily penetrates the skin, tea tree oil could be a useful agent in the treatment of eumycetoma.
Conclusions: Tea tree oil is active in vitro against M. mycetomatis. © The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.
Details
- Title
- In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin
- Authors/Creators
- W.W.J. van de Sande (Author/Creator)A.H. Fahal (Author/Creator)T.V. Riley (Author/Creator)H. Verbrugh (Author/Creator)A. van Belkum (Author/Creator)
- Publication Details
- Journal of Antimicrobial Chemotherapy, Vol.59(3), pp.553-555
- Publisher
- Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy
- Identifiers
- 991005543787407891
- Copyright
- © 2007 The Author
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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