Journal article
In vitro susceptibility of methicillin-resistant Staphylococcus aureus and methicillin-susceptible Staphylococcus aureus to a new antimicrobial, copper silicate
Antimicrobial Agents and Chemotherapy, Vol.51(12), pp.4505-4507
2007
Abstract
The soluble copper silicate (CS) MIC of 100 strains of methicillin- resistant Staphylococcus aureus and 100 strains of methicillin-susceptible S. aureus (MSSA) was 175 mg Cu/liter. Bactericidal and postantibiotic effects (≥1 h) were seen at 2x MIC and 4x MIC. The frequency of mutation was <10-9, and serial passage could not extend growth beyond 1.6 x MIC.
Details
- Title
- In vitro susceptibility of methicillin-resistant Staphylococcus aureus and methicillin-susceptible Staphylococcus aureus to a new antimicrobial, copper silicate
- Authors/Creators
- K.C. Carson (Author/Creator) - Pathwest Laboratory MedicineJ.G. Bartlett (Author/Creator) - Pathwest Laboratory MedicineT.-J. Tan (Author/Creator) - Pathwest Laboratory MedicineT.V. Riley (Author/Creator) - Queen Elizabeth II Medical Centre
- Publication Details
- Antimicrobial Agents and Chemotherapy, Vol.51(12), pp.4505-4507
- Publisher
- American Society for Microbiology
- Identifiers
- 991005543909707891
- Copyright
- © 2007 American Society for Microbiology
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.173 MRSA and VRE
- Web Of Science research areas
- Microbiology
- Pharmacology & Pharmacy
- ESI research areas
- Pharmacology & Toxicology