Journal article
Inbreeding and post-natal mortality in South India: Effects on the gene pool
Journal of Genetics, Vol.64(2-3), pp.135-142
1985
Abstract
Consanguineous marriages have been favoured throughout South India for many generations. On theoretical grounds it was proposed that long-term inbreeding would have resulted in the elimination of deleterious, recessive lethal and sub-lethal genes. As part of a newborn screening programme for amino acidopathies, data were collected on the level of inbreeding in the current populations of the cities of Bangalore and Mysore, and on the relationship between consanguinity and mean numbers of liveborn and living children. Mean cnonsanguinity was 32.24%, equivalent to a cuoefficient of inbreeding in the newborns,F = 00271. There were no significant differences between the various inbreeding classes in the number of liveborn or living children, nor was a significant consanguinity-related effect on the proportion of survivors detectable. In the light of these findings, the effects on the gene pool of multiple generations of inbreeding are discussed.
Details
- Title
- Inbreeding and post-natal mortality in South India: Effects on the gene pool
- Authors/Creators
- A.H. Bittles (Author/Creator)A.R. Devi (Author/Creator)H.S. Savithri (Author/Creator) - Indian Institute of Science BangaloreR. Sridhar (Author/Creator) - Indian Institute of Science BangaloreN.A. Rao (Author/Creator) - Indian Institute of Science Bangalore
- Publication Details
- Journal of Genetics, Vol.64(2-3), pp.135-142
- Publisher
- Springer
- Identifiers
- 991005542202207891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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