Incidence and prevalence of NMOSD in Australia and New Zealand

W. Bukhari; K.M. Prain; P. Waters; M. Woodhall; C.M. O‘Gorman; L. Clarke; R.A. Silvestrini; C.S. Bundell; D. Abernethy; S. Bhuta; S. Blum; M. Boggild; K. Boundy; B.J. Brew; M. Brown; W.J. Brownlee; H. Butzkueven; W.M. Carroll; C. Chen; A. Coulthard; R.C. Dale; C. Das; K. Dear; M.J. Fabis-Pedrini; D. Fulcher; D. Gillis; S. Hawke; R. Heard; A.P.D. Henderson; S. Heshmat; S. Hodgkinson; S. Jimenez-Sanchez; T. Killpatrick; J. King; C. Kneebone; A.J. Kornberg; J. Lechner-Scott; M. Lin; C. Lynch; R. Macdonell; D.F. Mason; P.A. McCombe; M.P. Pender; J.A. Pereira; J.D. Pollard; S.W. Reddel; C. Shaw; J. Spies; J. Stankovich; I. Sutton; S. Vucic; M. Walsh; R.C. Wong; E.M. Yiu; M.H. Barnett; A.G. Kermode; M.P. Marriott; J.D.E. Parratt; M. Slee; B.V. Taylor; E. Willoughby; R.J. Wilson; A. Vincent; S.A. Broadley

doi:10.1136/jnnp-2016-314839

Back

Incidence and prevalence of NMOSD in Australia and New Zealand

Journal article

Peer reviewed

Incidence and prevalence of NMOSD in Australia and New Zealand

W. Bukhari, K.M. Prain, P. Waters, M. Woodhall, C.M. O‘Gorman, L. Clarke, R.A. Silvestrini, C.S. Bundell, D. Abernethy, S. Bhuta, …

Journal of Neurology, Neurosurgery & Psychiatry, Vol.88(8), pp.632-638

2017

DOI: https://doi.org/10.1136/jnnp-2016-314839

Files and links (1)

url

Link to Published Version *Subscription may be requiredView

Abstract

OBJECTIVES: We have undertaken a clinic-based survey of neuromyelitis optica spectrum disorders (NMOSDs) in Australia and New Zealand to establish incidence and prevalence across the region and in populations of differing ancestry. BACKGROUND: NMOSD is a recently defined demyelinating disease of the central nervous system (CNS). The incidence and prevalence of NMOSD in Australia and New Zealand has not been established. METHODS: Centres managing patients with demyelinating disease of the CNS across Australia and New Zealand reported patients with clinical and laboratory features that were suspicious for NMOSD. Testing for aquaporin 4 antibodies was undertaken in all suspected cases. From this group, cases were identified who fulfilled the 2015 Wingerchuk diagnostic criteria for NMOSD. A capture-recapture methodology was used to estimate incidence and prevalence, based on additional laboratory identified cases. RESULTS: NMOSD was confirmed in 81/170 (48%) cases referred. Capture-recapture analysis gave an adjusted incidence estimate of 0.37 (95% CI 0.35 to 0.39) per million per year and a prevalence estimate for NMOSD of 0.70 (95% CI 0.61 to 0.78) per 100 000. NMOSD was three times more common in the Asian population (1.57 (95% CI 1.15 to 1.98) per 100 000) compared with the remainder of the population (0.57 (95% CI 0.50 to 0.65) per 100 000). The latitudinal gradient evident in multiple sclerosis was not seen in NMOSD. CONCLUSIONS: NMOSD incidence and prevalence in Australia and New Zealand are comparable with figures from other populations of largely European ancestry. We found NMOSD to be more common in the population with Asian ancestry.

Details

Title: Incidence and prevalence of NMOSD in Australia and New Zealand
Authors/Creators: W. Bukhari (Author/Creator) - Griffith University
K.M. Prain (Author/Creator)
P. Waters (Author/Creator) - John Radcliffe Hospital
M. Woodhall (Author/Creator) - John Radcliffe Hospital
C.M. O‘Gorman (Author/Creator)
L. Clarke (Author/Creator) - Griffith University
R.A. Silvestrini (Author/Creator) - Westmead Hospital
C.S. Bundell (Author/Creator) - The University of Western Australia
D. Abernethy (Author/Creator) - Wellington Hospital
S. Bhuta (Author/Creator) - Griffith University
S. Blum (Author/Creator) - Princess Alexandra Hospital
M. Boggild (Author/Creator) - Townsville Hospital
K. Boundy (Author/Creator) - Royal Adelaide Hospital
B.J. Brew (Author/Creator) - St Vincent's Health
M. Brown (Author/Creator) - Queensland University of Technology
W.J. Brownlee (Author/Creator)
H. Butzkueven (Author/Creator) - The University of Melbourne
W.M. Carroll (Author/Creator) - The University of Western Australia
C. Chen (Author/Creator) - Flinders Medical Centre
A. Coulthard (Author/Creator) - The University of Queensland
R.C. Dale (Author/Creator) - The University of Sydney
C. Das (Author/Creator) - Canberra Hospital
K. Dear (Author/Creator) - Duke University
M.J. Fabis-Pedrini (Author/Creator) - The University of Western Australia
D. Fulcher (Author/Creator) - The University of Sydney
D. Gillis (Author/Creator) - The University of Queensland
S. Hawke (Author/Creator) - The University of Sydney
R. Heard (Author/Creator) - The University of Sydney
A.P.D. Henderson (Author/Creator) - Westmead Hospital
S. Heshmat (Author/Creator) - Griffith University
S. Hodgkinson (Author/Creator) - UNSW Sydney
S. Jimenez-Sanchez (Author/Creator) - Griffith University
T. Killpatrick (Author/Creator) - Florey Institute of Neuroscience and Mental Health
J. King (Author/Creator) - Florey Institute of Neuroscience and Mental Health
C. Kneebone (Author/Creator) - Royal Adelaide Hospital
A.J. Kornberg (Author/Creator) - The University of Melbourne
J. Lechner-Scott (Author/Creator) - University of Newcastle Australia
M. Lin (Author/Creator) - The University of Sydney
C. Lynch (Author/Creator) - University of Auckland
R. Macdonell (Author/Creator)
D.F. Mason (Author/Creator) - Christchurch Hospital
P.A. McCombe (Author/Creator) - The University of Queensland
M.P. Pender (Author/Creator) - The University of Queensland
J.A. Pereira (Author/Creator) - University of Auckland
J.D. Pollard (Author/Creator) - The University of Sydney
S.W. Reddel (Author/Creator) - The University of Sydney
C. Shaw (Author/Creator) - Geelong Hospital
J. Spies (Author/Creator) - The University of Sydney
J. Stankovich (Author/Creator) - Menzies Research Institute
I. Sutton (Author/Creator) - St Vincent's Health
S. Vucic (Author/Creator) - Westmead Hospital
M. Walsh (Author/Creator) - The University of Queensland
R.C. Wong (Author/Creator) - The University of Queensland
E.M. Yiu (Author/Creator) - Royal Children's Hospital
M.H. Barnett (Author/Creator) - The University of Sydney
A.G. Kermode (Author/Creator) - The University of Western Australia
M.P. Marriott (Author/Creator) - The University of Melbourne
J.D.E. Parratt (Author/Creator)
M. Slee (Author/Creator) - Flinders Medical Centre
B.V. Taylor (Author/Creator) - Menzies Research Institute
E. Willoughby (Author/Creator)
R.J. Wilson (Author/Creator)
A. Vincent (Author/Creator) - John Radcliffe Hospital
S.A. Broadley (Author/Creator) - Griffith University
Publication Details: Journal of Neurology, Neurosurgery & Psychiatry, Vol.88(8), pp.632-638
Publisher: BMJ Publishing Group
Identifiers: 991005542338807891
Copyright: © 2017 Article author(s)
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

52 Record Views

97 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.203 Neuromuscular Disorders; 1.203.147 Multiple Sclerosis
Web Of Science research areas: Clinical Neurology; Psychiatry; Surgery
ESI research areas: Clinical Medicine