Individual- and Herd-Level Milk ELISA Test Status and Incidence for Paratuberculosis in Hubei Province, China

Yingyu Chen; Liyue Hou; Abdul Karim Khalid; Ian Duncan Robertson; Yuhao Zhao; Xi Chen; Aizhen Guo

doi:10.3390/vetsci11050202

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Individual- and Herd-Level Milk ELISA Test Status and Incidence for Paratuberculosis in Hubei Province, China

Journal article

Open access

Peer reviewed

Individual- and Herd-Level Milk ELISA Test Status and Incidence for Paratuberculosis in Hubei Province, China

Yingyu Chen, Liyue Hou, Abdul Karim Khalid, Ian Duncan Robertson, Yuhao Zhao, Xi Chen and Aizhen Guo

Veterinary sciences, Vol.11(5), 202

2024

DOI: https://doi.org/10.3390/vetsci11050202

PMID: 38787174

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Abstract

prevalence

incidence

bovine paratuberculosis

milk antibody ELISA

milk quality

Mycobacterium avium subsp. paratuberculosis (MAP) is responsible for the persistent infectious illness known as bovine paratuberculosis, which is one of the most easily overlooked diseases in China amid a lack of epidemiological data. In this study, we evaluated the agreement of milk and blood antibody tests for paratuberculosis and showed an overall agreement of 92.0%, with a 95.0% negative coincidence rate and a 78.6% positive coincidence rate. The milk test was then used to examine the prevalence and incidence of dairy cows in Hubei Province, China. We found that, at the individual level, the highest lacto-prevalence reached up to 22.9%; the farm-level prevalence was as high as 92.3% (12/13) and 84.6% (11/13) in January and April 2018, respectively. The total incidence risk of all farms was 6% per three months. We also found that large-scale farms had a significantly lower prevalence and incidence than small-scale farms. Finally, the correlation between paratuberculosis and milk quality was evaluated, and we confirmed that MAP can significantly alter milk quality and raise somatic cell counts in the milk. This study provides valuable information for assessing the prevalence and incidence risk of paratuberculosis in China. It further provides an essential basis for calling for the prevention and control of paratuberculosis in China.

Details

Title: Individual- and Herd-Level Milk ELISA Test Status and Incidence for Paratuberculosis in Hubei Province, China
Authors/Creators: Yingyu Chen - Huazhong Agricultural University
Liyue Hou - Huazhong Agricultural University
Abdul Karim Khalid - Huazhong Agricultural University
Ian Duncan Robertson - School of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia
Yuhao Zhao - Huazhong Agricultural University
Xi Chen - Huazhong Agricultural University
Aizhen Guo - Huazhong Agricultural University
Publication Details: Veterinary sciences, Vol.11(5), 202
Publisher: MDPI
Identifiers: 991005670269707891
Murdoch Affiliation: School of Veterinary Medicine
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

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#12 Responsible Consumption & Production

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.194 Tuberculosis & Leprosy; 1.194.273 TB Diagnostics & Treatment
Web Of Science research areas: Veterinary Sciences
ESI research areas: Plant & Animal Science