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Innovative approaches for treatment of osteosarcoma
Journal article   Peer reviewed

Innovative approaches for treatment of osteosarcoma

E. Rothzerg, A.L. Pfaff and S. Kõks
Experimental Biology and Medicine
2022
DOI: https://doi.org/10.1177/15353702211067718
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Abstract

Osteosarcoma (OS) is the most common primary malignant bone tumor, which usually occurs in children and adolescents. It is generally a high-grade malignancy presenting with extreme metastases to the lungs or other bones. The etiology of the disease is multifaceted and still remains obscure. A combination of surgery and chemotherapy has played a major role in the treatment of OS over the past three decades, and consequently, the overall survival rates for the disease have remained unchanged. Therefore, there is an urgent need to employ new comprehensive analyses and technologies to develop significantly more informative classification systems, with the aim of developing more effective and less toxic therapies for OS patients. This review discusses the existing knowledge of OS therapy and potential methods to develop novel therapeutic agents for the disease.

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UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

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72 Record Views
29 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.118 Soft Tissue, Bone & Nerve Cancers
1.118.300 Sarcoma Research
Web Of Science research areas
Medicine, Research & Experimental
ESI research areas
Clinical Medicine
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