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Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease
Journal article   Open access   Peer reviewed

Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease

K.J. Dunn, P.K. Nicholls, J.K. Dunn and M.E. Herrtage
Veterinary Record, Vol.136(25), pp.635-636
1995
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Abstract

Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count. Cytological examination of a sample of cerebrospinal fluid revealed evidence of haemorrhage and chronic inflammation. The levels of von Willebrand's factor antigen were extremely low. Skull radiographs were consistent with mild hydrocephalus. Treatment resulted in little clinical improvement and the animal was euthanased. Post mortem examination of the brain revealed an internal hydrocephalus with haemorrhage into the ventricles. It was considered that the animal had suffered severe intracranial haemorrhage as a result of its low level of von Willebrand's factor antigen and that the bleeding may have been potentiated by the low platelet count.

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Citation topics
1 Clinical & Life Sciences
1.103 Blood Disorders
1.103.1225 Immune Thrombocytopenia
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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