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Investigation of a Lomentospora prolificans case cluster with whole genome sequencing
Journal article   Open access   Peer reviewed

Investigation of a Lomentospora prolificans case cluster with whole genome sequencing

P. Boan, S. Pang, D.J. Gardam, H. Darragh, M. Wright and G.W. Coombs
Medical Mycology Case Reports, Vol.29, pp.1-4
2020
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Abstract

Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates from unrelated infections at Hospital 2., showing a high number of mutational differences (>10,000 single nucleotide polymorphisms) between L. prolificans isolates from Hospital 1. Novel typing of isolates by WGS did not demonstrate a single causative strain.

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