Journal article
Iron overload
Clinica Chimica Acta, Vol.358(1-2), pp.24-36
2005
Abstract
Iron overload disorders represent a heterogenous group of conditions resulting from inherited and acquired causes. With the discovery of new proteins and genetic defects we have gained greater insight into their causation at the molecular level and the complex mechanisms of normal and disordered iron homeostasis. Here we review the normal mechanisms and regulation of gastrointestinal iron absorption and liver iron transport and their dysregulation in iron overload states. Advances in the understanding of the natural history of iron overload disorders and new methods for clinical detection and management of hereditary hemochromatosis are also reviewed.
Details
- Title
- Iron overload
- Authors/Creators
- C.W. Siah (Author/Creator)D. Trinder (Author/Creator)J.K. Olynyk (Author/Creator)
- Publication Details
- Clinica Chimica Acta, Vol.358(1-2), pp.24-36
- Publisher
- Elsevier B.V.
- Identifiers
- 991005540190207891
- Copyright
- 2005 Elsevier B.V.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.184 Physiology & Metals
- 1.184.573 Iron Metabolism
- Web Of Science research areas
- Medical Laboratory Technology
- ESI research areas
- Clinical Medicine