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Isolation and selected properties of a molluscan ferritin with a low P/Fe ratio
Journal article   Peer reviewed

Isolation and selected properties of a molluscan ferritin with a low P/Fe ratio

K.S. Kim, J. Webb and D.J. Macey
Inorganica Chimica Acta, Vol.158(1), pp.127-129
1989
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Abstract

Ferritin has been isolated and characterized from the hemolymph of the limpet Patella laticostata. The intact protein was found to have a Mr of approx. 480 000 and be composed of a single subunit with an approx. Mr of 26 000. In addition, it possessed a pI of 6.6-6.8 despite displaying a low number of basic residues on amino acid determination. Chemical analysis revealed an iron to protein ratio of approx. 2000:1, while electron microscopy showed a core diameter of approx. 8 nm. Of particular interest is the extremely low phosphate to iron ratio which varied between 1:45 and 1:35 and which is far less than that reported for mammalian ferritins.

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Citation topics
1 Clinical & Life Sciences
1.184 Physiology & Metals
1.184.573 Iron Metabolism
Web Of Science research areas
Chemistry, Inorganic & Nuclear
ESI research areas
Chemistry
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