Journal article
Leflunomide-induced peripheral neuropathy
Journal of Clinical Neuroscience, Vol.14(2), pp.179-181
2007
Abstract
Two cases of leflunomide-induced peripheral neuropathy are described; in a 60-year-old woman with sero-negative polyarthralgia-myalgia syndrome and a 65-year-old man with sero-negative rheumatoid arthritis, both treated with leflunomide at 20 mg/day. Nerve conduction studies and electromyogram showed sensorimotor axonal neuropathy in both cases. An alternative cause for the axonal neuropathy was excluded by extensive investigations, including cerebrospinal fluid examination and nerve biopsy in the second patient. Both patients stabilized symptomatically and electrophysiologically upon cessation of leflunomide. It is possible that leflunomide-induced peripheral neuropathy has been under-reported and under-recognized.
Details
- Title
- Leflunomide-induced peripheral neuropathy
- Authors/Creators
- L.K. Kho (Author/Creator) - Royal Perth HospitalA.G. Kermode (Author/Creator) - Sir Charles Gairdner Hospital
- Publication Details
- Journal of Clinical Neuroscience, Vol.14(2), pp.179-181
- Publisher
- Churchill Livingstone
- Identifiers
- 991005544907407891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
34 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.106 Rheumatology
- 1.106.188 Rheumatoid Arthritis
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior