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Localization of methyl-coenzyme M reductase as metabolic marker for diverse methanogenic archaea
Journal article   Peer reviewed

Localization of methyl-coenzyme M reductase as metabolic marker for diverse methanogenic archaea

C. Wrede, U. Walbaum, A. Ducki, I. Heieren and M. Hoppert
Archaea, Vol.2013
2013
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Abstract

Methyl-Coenzyme M reductase (MCR) as key enzyme for methanogenesis as well as for anaerobic oxidation of methane represents an important metabolic marker for both processes in microbial biofilms. Here, the potential of MCR-specific polyclonal antibodies as metabolic marker in various methanogenic Archaea is shown. For standard growth conditions in laboratory culture, the cytoplasmic localization of the enzyme in Methanothermobacter marburgensis, Methanothermobacter wolfei, Methanococcus maripaludis, Methanosarcina mazei, and in anaerobically methane-oxidizing biofilms is demonstrated. Under growth limiting conditions on nickel-depleted media, at low linear growth of cultures, a fraction of 50-70% of the enzyme was localized close to the cytoplasmic membrane, which implies "facultative" membrane association of the enzyme. This feature may be also useful for assessment of growth-limiting conditions in microbial biofilms.

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UN Sustainable Development Goals (SDGs)

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#6 Clean Water and Sanitation
#7 Affordable and Clean Energy
#12 Responsible Consumption & Production

Source: InCites

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InCites Highlights

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.83 Bioengineering
3.83.416 Anaerobic Digestion
Web Of Science research areas
Microbiology
ESI research areas
Microbiology
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