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Long-term health risks for children and young adults after infective gastroenteritis
Journal article   Open access   Peer reviewed

Long-term health risks for children and young adults after infective gastroenteritis

R.E. Moorin, J.S. Heyworth, G.M. Forbes and T.V. Riley
Emerging Infectious Diseases, Vol.16(9), pp.1440-1447
2010
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Abstract

To quantify the risk and types of sequelae attributable to prior enteric infections, we undertook a population-based retrospective cohort study using linked administrative records. The risk for first-time hospitalization for sequelae was modeled by using Cox proportional regression analysis controlling for other health and sociodemographic factors. We identified a significant increase of 64% in the rate of first-time hospitalization for sequelae for persons with prior enteric infections: 52% for intragastrointestinal sequelae and 63% for extragastrointestinal sequelae compared with first-time hospitalization for those without prior infection. Extragastrointestinal sequelae occurred predominantly during the first 5 years after first-time enteric infection. In contrast, most intragastrointestinal sequelae occurred >10 years later. Infective gastroenteritis during childhood or adolescence increases the risk for first-time hospitalization for intragastrointestinal and extragastrointestinal disease over the 2 decades after first-time enteric infection, highlighting the importance of identifying ways of reducing the incidence of such infections.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.42 Bacteriology
1.42.376 Salmonella and Campylobacter
Web Of Science research areas
Immunology
Infectious Diseases
ESI research areas
Immunology
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