Journal article
Longitudinal study of pesticide residue levels in human milk from Western Australia during 12 months of lactation: Exposure assessment for infants
Scientific Reports, Vol.6
2016
Abstract
The presence of pesticides in human milk (HM) is of great concern due to the potential health effects for the breastfed infant. To determine the relationships between HM pesticides and infant growth and development, a longitudinal study was conducted. HM samples (n = 99) from 16 mothers were collected at 2, 5, 9 and 12 months of lactation. A validated QuEChERS method and Gas chromatography-tandem mass spectrometry (GC-MS/MS) were used for the analysis of 88 pesticides in HM. Only p,p'-DDE, p,p'-DDT and β-HCH were detected with a mean concentration (±SD) of 52.25 ± 49.88 ng/g fat, 27.67 ± 20.96 ng/g fat and 48.00 ± 22.46 ng/g fat respectively. The concentrations of the detected pesticides decreased significantly throughout the first year of lactation. No significant relationships between HM p,p'-DDE and infant growth outcomes: weight, length, head circumference and percentage fat mass were detected. The actual daily intake (ADI) of total DDTs in this cohort was 14-1000 times lower than the threshold reference and significantly lower than the estimated daily intake (EDI). Further, the ADI decreased significantly throughout the first 12 months of lactation.
Details
- Title
- Longitudinal study of pesticide residue levels in human milk from Western Australia during 12 months of lactation: Exposure assessment for infants
- Authors/Creators
- J. Du (Author/Creator) - The University of Western AustraliaZ. Gridneva (Author/Creator) - The University of Western AustraliaM.C.L. Gay (Author/Creator)C.T. Lai (Author/Creator) - The University of Western AustraliaR.D. Trengove (Author/Creator) - Murdoch UniversityP.E. Hartmann (Author/Creator) - The University of Western AustraliaD.T. Geddes (Author/Creator) - The University of Western Australia
- Publication Details
- Scientific Reports, Vol.6
- Publisher
- Nature Publishing Group
- Identifiers
- 991005542657607891
- Copyright
- © 2016 The Author(s)
- Murdoch Affiliation
- Separation Science and Metabolomics Laboratory
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.60 Herbicides, Pesticides & Ground Poisoning
- 3.60.221 Persistent Organic Pollutants
- Web Of Science research areas
- Environmental Sciences
- ESI research areas
- Environment/Ecology