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Longitudinal study of serum thyroid hormone levels during normal pregnancy
Journal article   Peer reviewed

Longitudinal study of serum thyroid hormone levels during normal pregnancy

P.C. O'Leary, P. Boyne, G. Atkinson, K.-J. Mileham and I. James
International Journal of Gynecology & Obstetrics, Vol.38(3), pp.171-179
1992
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Abstract

We undertook a prospective longitudinal study of thyroid function in 60 normal pregnant women and measured serum concentrations of T 4, triiodothyronine (T 3), T-uptake, thyroxine binding globulin (TBG), free thyroxine index (FTI), free T 4, albumin and thyrotropin (TSH). From these data we established reference ranges for each of these analytes for each trimester and examined the interrelationships between laboratory measurements of thyroid function tests. We observed significant increases in serum concentrations of thyrotropin and decreases in free T 4, assays commonly used as first line investigations of thyroid activity during pregnancy. However, the 95th centile intervals for both analytes remained within the reference range for nonpregnant women.

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#3 Good Health and Well-Being

Source: InCites

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.213 Thyroid Disorders
1.213.168 Thyroid Disorders
Web Of Science research areas
Obstetrics & Gynecology
ESI research areas
Clinical Medicine
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