Journal article
Loss of facial sweating and flushing in Holmes-Adie syndrome
Neurology, Vol.40(5), pp.847-849
1990
Abstract
We investigated pupillary responses to parasympathetic (pilocarpine) and sympathetic agents (tyramine, cocaine, and phenylephrine) in a 51-year-old woman with tonic pupils, loss of muscle stretch reflexes in the limbs, and hemifacial loss of sweating and flushing (Ross' syndrome). A smaller pupillary response to tyramine and cocaine eyedrops on the symptomatic side indicated that outflow was disrupted in the postganglionic section of the ocular sympathetic pathway. A greater response to phenylephrine eyedrops on this side was consistent with denervation supersensitivity to adrenergic agents. Loss of thermoregulatory sweating and flushing and emotional blushing in the forehead, cheek, and chin indicated that sympathetic disruption was proximal to the bifurcation of the common carotid artery, probably in the superior cervical ganglion. A similar degenerative process may be responsible for loss of muscle stretch reflexes, tonic pupils, and other autonomic disturbances in Ross' syndrome.
Details
- Title
- Loss of facial sweating and flushing in Holmes-Adie syndrome
- Authors/Creators
- P.D. Drummond (Author/Creator) - Murdoch UniversityR.H. Edis (Author/Creator)
- Publication Details
- Neurology, Vol.40(5), pp.847-849
- Publisher
- American Academy of Neurology
- Identifiers
- 991005541803907891
- Copyright
- © 1990 by the American Academy of Neurology
- Murdoch Affiliation
- School of Psychology
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.105 Strokes
- 1.105.1677 Cervical Artery Dissection
- Web Of Science research areas
- Clinical Neurology
- ESI research areas
- Neuroscience & Behavior