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Maceration of plant tissue by fungi is inhibited by recombinant antipectinase antibodies
Journal article   Peer reviewed

Maceration of plant tissue by fungi is inhibited by recombinant antipectinase antibodies

V. Manatunga, H. Sanati, P. Tan and P.A. O’Brien
European Journal of Plant Pathology, Vol.112(3), pp.211-220
2005
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Abstract

Polyclonal antiserum from mice immunized with extracellular proteins from Rhizoctonia solani inhibited pectinase and cellulase activities in cell free culture supernatants of Rhizoctonia solani. Spleen mRNA from these mice was used to construct a cDNA library from which antipectinase ScFv antibodies were isolated using phage display techniques. Soluble ScFv antibodies produced by individual clones in Escherichia coli inhibited polygalacturonase in the culture supernatants of a range of fungal pathogens, including ascomycetes, basidiomycetes, and oomycetes. The soluble antibodies also inhibited maceration of potato tissue by these pathogens.

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Collaboration types
International collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.4 Crop Science
3.4.1010 Plant Cell Walls
Web Of Science research areas
Agronomy
Horticulture
Plant Sciences
ESI research areas
Plant & Animal Science
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