Journal article
Mapping the evolutionary trajectories of morbilliviruses: What, where and whither
Current Opinion in Virology, Vol.16, pp.95-105
2016
Abstract
Morbilliviruses are pathogens of humans and other animals. Live attenuated morbillivirus vaccines have been used to end endemic transmission of measles virus (MV) in many parts of the developed world and to eradicate rinderpest virus. Entry is mediated by two different receptors which govern virus lymphotropism and epitheliotropism. Morbillivirus transmissibility is unparalleled and MV represents the most infectious human pathogen on earth. Their evolutionary origins remain obscure and their potential for adaption to new hosts is poorly understood. It has been suggested that MV could be eradicated. Therefore it is imperative to dissect barriers which restrict cross species infections. This is important as ecological studies identify novel morbilliviruses in a vast number of small mammals and carnivorous predators.
Details
- Title
- Mapping the evolutionary trajectories of morbilliviruses: What, where and whither
- Authors/Creators
- S. Nambulli (Author/Creator)C.R. Sharp (Author/Creator)A.S. Acciardo (Author/Creator)J.F. Drexler (Author/Creator)W.P. Duprex (Author/Creator)
- Publication Details
- Current Opinion in Virology, Vol.16, pp.95-105
- Publisher
- Elsevier
- Identifiers
- 991005542425807891
- Copyright
- © 2016 Elsevier B.V.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.104 Virology - General
- 1.104.568 Viral Disease Dynamics
- Web Of Science research areas
- Virology
- ESI research areas
- Microbiology