Journal article
Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography
The European respiratory journal, Vol.35(1), pp.34-41
2010
PMID: 19541718
Abstract
Airway dimensions are difficult to quantify bronchoscopically because of optical distortion and a limited ability to gauge depth. Anatomical optical coherence tomography (aOCT), a novel imaging technique, may overcome these limitations. This study evaluated the accuracy of aOCT against existing techniques in phantom, excised pig and in vivo human airways.
Three comparative studies were performed: 1) micrometer-derived area measurements in 10 plastic tubes were compared with aOCT-derived area; 2) aOCT-derived airway compliance curves from excised pig airways were compared with curves derived using an endoscopic technique; and 3) airway dimensions from the trachea to subsegmental bronchi were measured using aOCT in four anaesthetised patients during bronchoscopy and compared with computed tomography (CT) measurements.
Measurements in plastic tubes revealed aOCT to be accurate and reliable. In pig airways, aOCT-derived compliance measurements compared closely with endoscopic data. In human airways, dimensions measured with aOCT and CT correlated closely. Bland–Altman plots showed that aOCT diameter and area measurements were higher than CT measurements by 7.6% and 15.1%, respectively.
Airway measurements using aOCT are accurate, reliable and compare favourably with existing imaging techniques. Using aOCT with conventional bronchoscopy allows real-time measurement of airway dimensions and could be useful clinically in settings where knowledge of airway calibre is required.
Details
- Title
- Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography
- Authors/Creators
- J. P. Williamson - School of Anatomy, Physiology and Human BiologyJ. J. Armstrong - School of Electrical, Electronic and Computer EngineeringR. A. McLaughlin - School of Electrical, Electronic and Computer EngineeringP. B. Noble - Telethon Inst Child Hlth Res, Div Clin Sci, Perth, WA, AustraliaA. R. West - School of Molecular SciencesS. Becker - School of Electrical, Electronic and Computer EngineeringA. Curatolo - School of Electrical, Electronic and Computer EngineeringW. J. Noffsinger - Sir Charles Gairdner Hosp, Dept Pulm Physiol, Perth, WA 6000, AustraliaH. W. Mitchell - School of Molecular SciencesM. J. Phillips - College Station Medical CenterD. D. Sampson - School of Electrical, Electronic and Computer EngineeringD. R. Hillman - Sir Charles Gairdner Hosp, Dept Pulm Physiol, Perth, WA 6000, AustraliaP. R. Eastwood - School of Anatomy, Physiology and Human Biology
- Publication Details
- The European respiratory journal, Vol.35(1), pp.34-41
- Publisher
- European Respiratory Soc Journals Ltd
- Number of pages
- 8
- Grant note
- University of Western Australia Raine Medical Research Foundation (Nedlands, Australia) Sir Charles Gairdner Hospital 513854; 463926; 513704 / National Health and Medical Research Council (NHMRC; Canberra, Australia); National Health and Medical Research Council of Australia 513921 / Australian-based Biomedical Fellowship Research Grant
- Identifiers
- 991005591573107891
- Copyright
- © ERS Journals Ltd 2010
- Murdoch Affiliation
- Vice Chancellery
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Citation topics
- 5 Physics
- 5.250 Imaging & Tomography
- 5.250.1350 Optical Coherence Tomography
- Web Of Science research areas
- Respiratory System
- ESI research areas
- Clinical Medicine