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Medium-chain fatty acids for the prevention or treatment of Alzheimer's disease: A systematic review and meta-analysis
Journal article   Peer reviewed

Medium-chain fatty acids for the prevention or treatment of Alzheimer's disease: A systematic review and meta-analysis

C. Castro, C. Dias, H. Sohrabi, T. Shah, P. Chatterjee, H. Hillebrandt, S. Fuller, M. Garg and R. Martins
Journal of the American Oil Chemists Society, Vol.99(Suppl. 1)
2022
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Abstract

In preclinical AD, the brain gradually becomes insulin resistant causing a cellular energy deficit, which leads to the accumulation of free radicals increasing inflammation and damaging neurons, thus ketone bodies offer an alternative energy source having the potential to supply the insulin-resistant brain with energy and may improve cognition.

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