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Mercury(II) mediated cyclisation of R-1-(1′-hydroxyethyl)-2-(1″-propenyl)-3-alkoxy-4-methoxybenzenes to chiral isochromanes
Journal article   Peer reviewed

Mercury(II) mediated cyclisation of R-1-(1′-hydroxyethyl)-2-(1″-propenyl)-3-alkoxy-4-methoxybenzenes to chiral isochromanes

C.B. de Koning, R.G.F. Giles, I.R. Green and N.M. Jahed
Tetrahedron, Vol.60(11), pp.2629-2637
2004
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Abstract

A protocol has been established for the transformation of chiral ortho 1-hydroxyethyl propenyl benzenes under both anaerobic and oxidative mercury(II) mediated conditions to produce chiral isochromanes. Further transformations of the former products yielded chiral isochromanquinones, while the latter afforded the corresponding chiral 4-hydroxyisochromanquinones.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.219 Cancer Drugs
1.219.1527 Naphthoquinone Derivatives
Web Of Science research areas
Chemistry, Organic
ESI research areas
Chemistry
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