Journal article
Methicillin-resistant Staphylococcus aureus clones, Western Australia
Emerging Infectious Diseases, Vol.12(2), pp.241-247
2006
Abstract
Community-associated methicillin-resistant Staphylococcus aureus (MRSA) was first reported in Western Australia in the early 1990s from indigenous peoples living in remote areas. Although a statewide policy of screening all hospital patients and staff who have lived outside the state for MRSA has prevented the establishment of multidrug-resistant epidemic MRSA, the policy has not prevented SCCmec type IV and type V MRSA clones from becoming established. Of the 4,099 MRSA isolates analyzed (referred to the Gram-positive Bacteria Typing and Research Unit) from July 2003 to December 2004, 77.5% were community-associated MRSA (CA-MRSA). Using multilocus sequence/staphylococcal chromosome cassette mec typing, 22 CA-MRSA clones were characterized. Of these isolates, 55.5% were resistant to >1 non–β-lactam antimicrobial drug. Five Panton-Valentine leukocidin (PVL)–positive CA-MRSA clones were identified. The emergence of multidrug-resistant CA-MRSA clones and the detection of PVL toxin genes in clones previously reported as PVL negative is a major public health concern.
Details
- Title
- Methicillin-resistant Staphylococcus aureus clones, Western Australia
- Authors/Creators
- G.W. Coombs (Author/Creator) - Royal Perth HospitalJ.C. Pearson (Author/Creator) - Royal Perth HospitalF.G. O'Brien (Author/Creator) - Curtin UniversityR.J. Murray (Author/Creator) - Royal Perth HospitalW.B. Grubb (Author/Creator) - Curtin UniversityK.J. Christiansen (Author/Creator) - Curtin University
- Publication Details
- Emerging Infectious Diseases, Vol.12(2), pp.241-247
- Publisher
- National Center for Infectious Diseases
- Identifiers
- 991005543583507891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
Metrics
126 File views/ downloads
63 Record Views