Journal article
Molecular and biological characterisation of Cryptosporidium in pigs.
Australian Veterinary Journal, Vol.77(1), pp.44-47
01/1999
Abstract
OBJECTIVE: Genetic and biological characterisation of 12 isolates of Cryptosporidium from pigs and comparing them with Cryptosporidium isolates from humans and cattle. DESIGN: Cryptosporidium isolates from pigs were compared with those obtained from human and cattle using rDNA sequence analysis. The infectivity of two of the porcine isolates was determined in neonatal mice and the clinical history of the infected pigs recorded. RESULTS: Pig-derived isolates of Cryptosporidium exhibited two distinct genotypes; a porcine genotype and a bovine genotype, which is common to cattle and other livestock. The porcine genotype did not produce any infection in neonatal mice whereas the bovine genotype did. CONCLUSION: Two distinct genetically and biologically differing strains of Cryptosporidium appeared to be associated with acute diarrhoea in pigs. Whether Cryptosporidium was a primary or secondary pathogen is unclear but warrants further investigation. As the bovine genotype is known to infect humans, the results suggest that pigs can act as reservoirs of cryptosporidial infections for humans and other live-stock. The zoonotic potential of the pig-adapted genotype is uncertain and requires further study.
Details
- Title
- Molecular and biological characterisation of Cryptosporidium in pigs.
- Authors/Creators
- U.M. Morgan (Author/Creator)J.R. Buddle (Author/Creator)A. Armson (Author/Creator)A. Elliot (Author/Creator)R.C.A. Thompson (Author/Creator)
- Publication Details
- Australian Veterinary Journal, Vol.77(1), pp.44-47
- Publisher
- Wiley-Blackwell
- Identifiers
- 991005541888507891
- Copyright
- © 1999
- Murdoch Affiliation
- State Agricultural Biotechnology Centre; School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science