Journal article
Molecular characterization of Cryptosporidium spp. from wild rats and mice from rural communities in the Philippines
Infection, Genetics and Evolution, Vol.16, pp.5-12
2013
Abstract
In order to examine the prevalence of Cryptosporidium in wild rodents in the Philippines and understand the role wild rodents play in the transmission of this parasite to humans and livestock, 194 fecal samples from wild rats and mice from Luzon and Mindoro islands were examined. Molecular screening at the 18S and actin gene loci identified an overall prevalence of 25.8% (95%CI: 19.8, 32.5). Sequence and phylogenetic analysis of both loci identified C. parvum, C. muris, C. scrofarum, rat genotypes I-IV and a C. suis-like genotype in the rat-derived isolates and is the first report of C. suis-like and C. scrofarum in rats. Mixed infections were identified in 24% of the Cryptosporidium positive isolates. Rat genotypes II, III and IV showed high intragenotypic variation at the 18S gene locus compared to the actin locus.
Details
- Title
- Molecular characterization of Cryptosporidium spp. from wild rats and mice from rural communities in the Philippines
- Authors/Creators
- J.S.Y. Ng-Hublin (Author/Creator)G.R. Singleton (Author/Creator) - International Rice Research InstituteU. Ryan (Author/Creator) - Murdoch University
- Publication Details
- Infection, Genetics and Evolution, Vol.16, pp.5-12
- Publisher
- Elsevier BV
- Identifiers
- 991005543981807891
- Copyright
- © 2013 Elsevier B.V.
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences; School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Infectious Diseases
- ESI research areas
- Molecular Biology & Genetics