Journal article
Molecular epidemiology: A multidisciplinary approach to understanding parasitic zoonoses
International Journal for Parasitology, Vol.35(11-12), pp.1295-1307
2005
Abstract
Sound application of molecular epidemiological principles requires working knowledge of both molecular biological and epidemiological methods. Molecular tools have become an increasingly important part of studying the epidemiology of infectious agents. Molecular tools have allowed the aetiological agent within a population to be diagnosed with a greater degree of efficiency and accuracy than conventional diagnostic tools. They have increased the understanding of the pathogenicity, virulence, and host-parasite relationships of the aetiological agent, provided information on the genetic structure and taxonomy of the parasite and allowed the zoonotic potential of previously unidentified agents to be determined. This review describes the concept of epidemiology and proper study design, describes the array of currently available molecular biological tools and provides examples of studies that have integrated both disciplines to successfully unravel zoonotic relationships that would otherwise be impossible utilising conventional diagnostic tools. The current limitations of applying these tools, including cautions that need to be addressed during their application are also discussed.
Details
- Title
- Molecular epidemiology: A multidisciplinary approach to understanding parasitic zoonoses
- Authors/Creators
- R.J. Traub (Author/Creator) - Murdoch UniversityP.T. Monis (Author/Creator) - South Australian Water CorporationI.D. Robertson (Author/Creator) - Murdoch University
- Publication Details
- International Journal for Parasitology, Vol.35(11-12), pp.1295-1307
- Publisher
- Elsevier BV
- Identifiers
- 991005545246607891
- Copyright
- © 2005 Australian Society for Parasitology Inc.
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Parasitology
- ESI research areas
- Microbiology