Journal article
Molecular variation in Giardia
Acta Tropica, Vol.53(3-4), pp.167-184
1993
Abstract
Molecular characterisation of species within the genus Giardia has revealed that much of the phenotypic heterogeneity, particularly within the species G. duodenalis, has a genetic basis. The source of this genetic variation appears to arise from predominantly asexual, clonal reproduction, although occasional bouts of sexual reproduction cannot be ruled out. Genetic variation is extensive with some clones widely distributed and others seemingly unique and localised to a particular endemic focus. Little attention has been given to the molecular epidemiology of Giardia infections. Future studies should be directed at studying the ecology and dynamics of transmission of Giardia clones, particularly in localised areas, and to evaluating the factors that serve to maintain genetic diversity between clones, especially the role of inter-clonal competition. Future research using molecular techniques should aim to identify and follow Giardia clones in nature and correlate genetic typing with important clinical and epidemiological characteristics such as virulence, drug sensitivity and zoonotic potential.
Details
- Title
- Molecular variation in Giardia
- Authors/Creators
- R.C.A. Thompson (Author/Creator) - Murdoch UniversityB.P. Meloni (Author/Creator) - Murdoch University
- Publication Details
- Acta Tropica, Vol.53(3-4), pp.167-184
- Publisher
- Elsevier BV
- Identifiers
- 991005541088907891
- Copyright
- © 1993 Published by Elsevier B.V.
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
23 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Parasitology
- Tropical Medicine
- ESI research areas
- Clinical Medicine