Journal article
Motor cortex reorganisation in Parkinson’s disease
Journal of Clinical Neuroscience, Vol.13(6), pp.639-642
2006
Abstract
Transcranial magnetic stimulation mapping of the motor cortical projection to the hand was performed in a group of patients with Parkinson’s disease (PD) of variable duration to determine whether there is evidence of cortical reorganisation. Map shifts were found in the majority of PD cases (12/15), in untreated early cases as well as treated cases of longer duration, and there was a correlation between inter-side difference in the severity of PD symptoms (Unified Parkinson’s Disease Rating Scale) and interhemispheric map displacement (r = 0.60; P = 0.018). These findings indicate that there is reorganisation of the corticomotor representation of the hand in PD, even at a relatively early stage of the disease, and suggest a dynamic process of reorganisation in the motor cortex due to an increase in the pallidal inhibitory inputs to the thalamo-cortical projections.
Details
- Title
- Motor cortex reorganisation in Parkinson’s disease
- Authors/Creators
- G.W. Thickbroom (Author/Creator) - Queen Elizabeth II Medical CentreM.L. Byrnes (Author/Creator) - Queen Elizabeth II Medical CentreS. Walters (Author/Creator) - Queen Elizabeth II Medical CentreR. Stell (Author/Creator) - Queen Elizabeth II Medical CentreF.L. Mastaglia (Author/Creator) - Queen Elizabeth II Medical Centre
- Publication Details
- Journal of Clinical Neuroscience, Vol.13(6), pp.639-642
- Publisher
- Churchill Livingstone
- Identifiers
- 991005541139807891
- Copyright
- © 2006 Published by Elsevier Ltd
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
84 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.82 Gait & Posture
- 1.82.811 Transcranial Magnetic Stimulation
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior