Journal article
Mouse respiratory tract dendritic cell subsets and the immunological fate of inhaled antigens
Immunology and Cell Biology, Vol.85, pp.182-188
2007
Abstract
It is widely accepted that tissue dendritic cells (DC) function as immune sentinels by alerting T cells to foreign antigen after delivering and presenting it in the draining lymph nodes. Over the last two decades, studies in animal models, particularly rodents, have demonstrated that respiratory tract DC are crucial for the adaptive immune response to inhaled antigen. Indeed, the fate of inhaled antigen is inextricably linked to the function of respiratory tract DC. In this review, we will discuss the characteristics of respiratory tract DC from mice and recent data that may help to explain their role in the fate of inhaled antigen.
Details
- Title
- Mouse respiratory tract dendritic cell subsets and the immunological fate of inhaled antigens
- Authors/Creators
- M.E. Wikstrom (Author/Creator)P.A. Stumbles (Author/Creator)
- Publication Details
- Immunology and Cell Biology, Vol.85, pp.182-188
- Publisher
- Nature Publishing Group
- Identifiers
- 991005541701407891
- Copyright
- 2007 Australasian Society for Immunology Inc.
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.6 Immunology
- 1.6.358 Dendritic Cell Therapy
- Web Of Science research areas
- Cell Biology
- Immunology
- ESI research areas
- Immunology