Multilocus genotypic analysis of Cryptosporidium parvum isolates from different hosts and geographical origins.

F. Spano; L. Putignani; A. Crisanti; P. Sallicandro; U.M. Morgan; S.M. Le Blancq; L. Tchack; S. Tzipori; G. Widmer

Back

Multilocus genotypic analysis of Cryptosporidium parvum isolates from different hosts and geographical origins.

Journal article

Open access

Peer reviewed

Multilocus genotypic analysis of Cryptosporidium parvum isolates from different hosts and geographical origins.

F. Spano, L. Putignani, A. Crisanti, P. Sallicandro, U.M. Morgan, S.M. Le Blancq, L. Tchack, S. Tzipori and G. Widmer

Journal of Clinical Microbiology, Vol.36(11), pp.3255-3259

11/1998

Files and links (1)

pdf

multilocus_genotypic_analysis_of_cryptosporidium_parvum_isolates.pdfDownload View

Published (Version of Record) Open Access

Abstract

The genetic analysis of oocysts recovered from the stools of humans and animals infected with Cryptosporidium parvum has consistently shown the existence of two distinct genotypes. One of the genotypes is found exclusively in some human infections, whereas the other genotype is found in human as well as in animal infections. On the basis of these observations and the results of published epidemiological studies with single polymorphic markers, the existence of two separate transmission cycles has been postulated, one exclusively anthroponotic and the other involving both animals and humans. To test this hypothesis, C. parvum isolates of different geographic and host origins were analyzed by using unlinked genetic polymorphisms. A total of 28 isolates originating from Europe, North and South America, and Australia were examined. Isolates clustered into two groups, one comprising both human and animal isolates and the other comprising isolates only of human origin. The absence of recombinant genotypes is consistent with two reproductively isolated populations within the species C. parvum.

Details

Title: Multilocus genotypic analysis of Cryptosporidium parvum isolates from different hosts and geographical origins.
Authors/Creators: F. Spano (Author/Creator)
L. Putignani (Author/Creator)
A. Crisanti (Author/Creator)
P. Sallicandro (Author/Creator)
U.M. Morgan (Author/Creator)
S.M. Le Blancq (Author/Creator)
L. Tchack (Author/Creator)
S. Tzipori (Author/Creator)
G. Widmer (Author/Creator)
Publication Details: Journal of Clinical Microbiology, Vol.36(11), pp.3255-3259
Publisher: American Society for Microbiology
Identifiers: 991005543872907891
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Language: English
Resource Type: Journal article
Publisher URL: http://jcm.asm.org/content/36/11/3255.full.pdf+html

Metrics

102 File views/ downloads

46 Record Views