NMOSD acute attack: Understanding, treatment and innovative treatment prospect

X. Ma; A.G. Kermode; X. Hu; W. Qiu

doi:10.1016/j.jneuroim.2020.577387

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NMOSD acute attack: Understanding, treatment and innovative treatment prospect

Journal article

Peer reviewed

NMOSD acute attack: Understanding, treatment and innovative treatment prospect

X. Ma, A.G. Kermode, X. Hu and W. Qiu

Journal of Neuroimmunology, Vol.348, Art. 577387

2020

DOI: https://doi.org/10.1016/j.jneuroim.2020.577387

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Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a group of severe inflammatory demyelinating disorders of the central nervous system that involves the optic nerve and spinal cord. Currently the therapeutic options for an acute attack in NMOSD are limited and rarely characterized in clinical studies. This review discussed the overall characteristics of acute attack of NMOSD, related risk factor, prognosis and management. Considering the huge unmet needs and the emergence of new therapeutic targets, we also reviewed innovative treatments that might alleviate attack damage, along with the challenges to evaluate new drug for acute attack in NMOSD.

Details

Title: NMOSD acute attack: Understanding, treatment and innovative treatment prospect
Authors/Creators: X. Ma (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
A.G. Kermode (Author/Creator) - Sun Yat-sen University
X. Hu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
W. Qiu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
Publication Details: Journal of Neuroimmunology, Vol.348, Art. 577387
Publisher: Elsevier
Identifiers: 991005542438607891
Copyright: © 2020 Elsevier B.V.
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.203 Neuromuscular Disorders; 1.203.147 Multiple Sclerosis
Web Of Science research areas: Immunology; Neurosciences
ESI research areas: Neuroscience & Behavior