Journal article
Next-Generation Nucleic Acid Aptamers with Two-Base-Modified Nucleotides Have Improved Binding Affinity and Potency
ChemBioChem, Vol.18(16), pp.1565-1567
26/06/2017
Abstract
Twice as apt: Nucleic acid aptamers with high binding affinity, specificity, epitope coverage and nuclease resistance were developed by using libraries containing oligonucleotides in which two bases in the pyrimidine nucleotide had been modified.
Details
- Title
- Next-Generation Nucleic Acid Aptamers with Two-Base-Modified Nucleotides Have Improved Binding Affinity and Potency
- Authors/Creators
- H. Al Shamaileh (Author/Creator)R.N. Veedu (Author/Creator) - Murdoch University
- Publication Details
- ChemBioChem, Vol.18(16), pp.1565-1567
- Publisher
- Wiley
- Identifiers
- 991005540388807891
- Copyright
- © 2017 John Wiley & Sons, Inc.
- Murdoch Affiliation
- Centre for Comparative Genomics
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
145 File views/ downloads
97 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 2 Chemistry
- 2.145 Biosensors
- 2.145.243 Nanobiosensors
- Web Of Science research areas
- Biochemistry & Molecular Biology
- Chemistry, Medicinal
- ESI research areas
- Biology & Biochemistry