Not to be suppressed? Rethinking the host response at a root-parasite interface

D.B. Goto; H. Miyazawa; J.C. Mar; M. Sato

doi:10.1016/j.plantsci.2013.08.004

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Not to be suppressed? Rethinking the host response at a root-parasite interface

Journal article

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Not to be suppressed? Rethinking the host response at a root-parasite interface

D.B. Goto, H. Miyazawa, J.C. Mar and M. Sato

Plant Science, Vol.213, pp.9-17

2013

DOI: https://doi.org/10.1016/j.plantsci.2013.08.004

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Abstract

Root-knot nematodes are highly efficient plant parasites that establish permanent feeding sites within host roots. The initiation of this feeding site is critical for parasitic success and requires an interaction with multiple signaling pathways involved in plant development and environmental response. Resistance against root-knot nematodes is relatively rare amongst their broad host range and they remain a major threat to agriculture. The development of effective and sustainable control strategies depends on understanding how host signaling pathways are manipulated during invasion of susceptible hosts. It is generally understood that root-knot nematodes either suppress host defense signaling during infestation or are able to avoid detection altogether, explaining their profound success as parasites. However, when compared to the depth of knowledge from other well-studied pathogen interactions, the published data on host responses to root-knot nematode infestation do not yet provide convincing support for this hypothesis and alternative explanations also exist. It is equally possible that defense-like signaling responses are actually induced and required during the early stages of root-knot nematode infestation. We describe how defense-signaling is highly context-dependent and that caution is necessary when interpreting transcriptional responses in the absence of appropriate control data or stringent validation of gene annotation. Further hypothesis-driven studies on host defense-like responses are required to account for these limitations and advance our understanding of root-knot nematode parasitism of plants.

Details

Title: Not to be suppressed? Rethinking the host response at a root-parasite interface
Authors/Creators: D.B. Goto (Author/Creator) - Hokkaido University
H. Miyazawa (Author/Creator) - Hokkaido University
J.C. Mar (Author/Creator) - Albert Einstein College of Medicine
M. Sato (Author/Creator) - National Institute for Basic Biology
Publication Details: Plant Science, Vol.213, pp.9-17
Publisher: Elsevier
Identifiers: 991005544054507891
Copyright: © 2013 Elsevier Ireland Ltd.
Murdoch Affiliation: School of Veterinary and Life Sciences
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 3 Agriculture, Environment & Ecology; 3.97 Plant Pathology; 3.97.1108 Nematode Management
Web Of Science research areas: Biochemistry & Molecular Biology; Plant Sciences
ESI research areas: Plant & Animal Science