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Journal article
Osteoblastic metastasis secondary to mammary carcinoma in a dog (canis lupus familiaris) presenting with lameness
Veterinary record case reports
2025
Abstract
Osteoblastic metastases occur secondary to malignant epithelial tumours, and lead to marked periosteal hyperostosis and medullary sclerosis. These are rarely reported in dogs. A 7-year-old, neutered, female labrador retriever × standard poodle presented with a 4-week history of progressive right hindlimb lameness, pyrexia and thoracolumbar pain. A mammary mass was identified, with cytology indicating a malignant carcinoma. Computed tomography demonstrated extensive primary osteoblastic lesions affecting vertebrae and proximal appendicular bones, alongside pulmonary and lymph node metastasis. Given the guarded prognosis, euthanasia was elected by the owner. Postmortem examination revealed irregular periosteal proliferation associated with metastatic mammary carcinoma in the scapula, humerus, femur, ribs, thoracic and lumbar vertebrae and bony induration of the medulla of the long bones. This case advances the understanding of skeletal metastases in dogs, which can often be misdiagnosed, and offers guidance for clinical and diagnostic approaches.
Details
- Title
- Osteoblastic metastasis secondary to mammary carcinoma in a dog (canis lupus familiaris) presenting with lameness
- Authors/Creators
- David Sheehan - University College DublinBenoit Cuq - Small Animal Internal Medicine, University College Dublin, School of Veterinary Medicine, Veterinary Science Centre, Belfield, Dublin, IrelandConor Moloney - University of LiverpoolSeamus Hoey - University College DublinOliver Waite - Murdoch University, School of Veterinary MedicineHanne Jahns - University College Dublin
- Publication Details
- Veterinary record case reports
- Publisher
- John Wiley & Sons Ltd on behalf of British Veterinary Association.
- Number of pages
- 5
- Identifiers
- 991005829249407891
- Copyright
- © 2025 The Author(s).
- Murdoch Affiliation
- Murdoch University; School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
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