Journal article
P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy
Retrovirology, Vol.6(Suppl 3, 22 October 2009), P128
2009
Abstract
Loss of immune reactivity due to HIV mutational escape is well described. Data generated from a large population-based study (n>800) suggested that certain CD8 T cell epitopes are created as a result of HIV adaptation and are associated with enhanced viral replication. Here we sought to investigate the HLA-restricted T-cell responses associated with seven such adaptations.
Details
- Title
- P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy
- Authors/Creators
- N.M. Keane (Author/Creator) - Royal Perth HospitalS.G. Roberts (Author/Creator) - Royal Perth HospitalR. Laird (Author/Creator) - Royal Perth HospitalA. Chopra (Author/Creator) - Royal Perth HospitalT. Krishnan (Author/Creator) - Royal Perth HospitalC.M. Almeida (Author/Creator)C. Bronke (Author/Creator) - Royal Perth HospitalS. Mallal (Author/Creator) - Royal Perth HospitalI. James (Author/Creator) - Royal Perth HospitalM. John (Author/Creator) - Royal Perth Hospital
- Publication Details
- Retrovirology, Vol.6(Suppl 3, 22 October 2009), P128
- Publisher
- BioMed Central
- Identifiers
- 991005545118507891
- Copyright
- © 2009 Keane et al
- Murdoch Affiliation
- Centre for Clinical Immunology and Biomedical Statistics
- Language
- English
- Resource Type
- Journal article
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- Web Of Science research areas
- Virology
- ESI research areas
- Microbiology