Journal article
Pancreatic response in healthy dogs fed diets of various fat compositions
American Journal of Veterinary Research, Vol.70(5), pp.614-618
2009
Abstract
Objective - To indirectly assess the pancreatic response in healthy dogs that were fed diets of different fat compositions with or without supplemental pancreatic enzymes and medium-chain triglycerides (MCTs). Animals - 10 healthy adult dogs. Procedures - Dogs were fed 4 diets once in random order at 1-week intervals; food was withheld from the dogs for ≥ 12 hours prior to the feeding of each diet. Diets A and B contained 16% and 5% crude fat, respectively; diet C was composed of diet A with pancreatic enzymes; and diet D was composed of diet B with pancreatic enzymes and MCTs. Serum canine trypsin-like immunoreactivity (cTLI) and canine pancreatic lipase immunoreactivity (cPLI) concentrations were measured before (0 hours) and at 1 to 2 and 6 hours after feeding. Serum gastrin concentration was measured at 0 hours and at 5 to 10 minutes and 1 to 2 hours after feeding. A gastrin assay validation study was performed to confirm accuracy of test results in dogs. Data were analyzed by use of a repeated-measures general ANOVA. Results - Serum cTLI, cPLI, or gastrin concentrations in the dogs did not differ among the different diets fed, among dogs, or over time. When multiple comparisons were analyzed, diet D caused the least amount of measurable pancreatic response, although this difference was not significant. Conclusions and Clinical Relevance - Results did not indicate a significant effect of dietary fat content or addition of supplemental MCT oil or pancreatic enzymes in diets on serum cTLI, cPLI, or gastrin concentrations in healthy dogs.
Details
- Title
- Pancreatic response in healthy dogs fed diets of various fat compositions
- Authors/Creators
- F.E. James (Author/Creator)C.S. Mansfield (Author/Creator)J.M. Steiner (Author/Creator)D.A. Williams (Author/Creator)I.D. Robertson (Author/Creator)
- Publication Details
- American Journal of Veterinary Research, Vol.70(5), pp.614-618
- Publisher
- American Veterinary Medical Association
- Identifiers
- 991005544626507891
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.151 Pancreas & Gall Bladder Disorders
- 1.151.676 Pancreatitis
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science