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Parkinsonism–hyperpyrexia syndrome: The role of electroconvulsive therapy
Journal article   Peer reviewed

Parkinsonism–hyperpyrexia syndrome: The role of electroconvulsive therapy

L.J. Meagher, D. McKay, G.K. Herkes and M. Needham
Journal of Clinical Neuroscience, Vol.13(8), pp.857-859
2006
DOI: https://doi.org/10.1016/j.jocn.2005.09.017
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Abstract

Herein, we present a case of a parkinsonism–hyperpyrexia syndrome (PHS) in a 58-year-old man with a 10-year history of Parkinson’s disease. The patient presented with a 2-week history of fever and increasing confusion, in the context of a number of changes to his medication regimen. On presentation, he was noted to be febrile with autonomic instability, diaphoresis and marked rigidity. He was disoriented and responding to visual hallucinations. Investigations revealed an elevated creatine kinase and a provisional diagnosis of PHS was made. After the patient failed to respond during a 2-week period to supportive measures, electroconvulsive therapy (ECT) treatment was commenced. A good response to eight bilateral ECT treatments was achieved, with resolution of his confusional state and associated psychotic phenomena. We discuss the nosological and management issues associated with this case and discuss the role of ECT as a treatment modality in this condition.

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Source: InCites

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.21 Psychiatry
1.21.1604 Electroconvulsive Therapy
Web Of Science research areas
Clinical Neurology
Neurosciences
ESI research areas
Neuroscience & Behavior
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